Kojic acid CAS# 501-30-4

Name: Kojic acid CAS# 501-30-4
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Kojic acid CAS# 501-30-4

Kojic acid (CAS# 501-30-4) is a natural compound produced by microbial fermentation and is commonly found in the metabolites of Aspergillus and penicillium fungi. The chemical name was 5-hydroxy-2-hydroxymethyl-4h-pyrano-4-one. The molecular form was ₆. H₆O₄, and the molecular weight was 142.11. Kojic acid has a certain acidity and is relatively stable in acidic and neutral environments. It can chelate with metal ions and affect the activity of some enzymes, especially related to tyrosinase, which can reduce the production of melanin by inhibiting the activity of the enzyme, and is often used in the field of whitening skin care. In the food industry, due to its antioxidant properties, it can prevent food Browning and extend the shelf life.

Product Name:	Kojic acid
Synonyms:	4H-Pyran-4-one, 5-hydroxy-2-(hydroxymethyl)-;4H-Pyran-4-one,5-hydroxy-2-(hydroxymethyl)-;5-hydroxy-2-(hydroxymethyl)-4h-pyran-4-on;kojic;Pyran-4-one, 5-hydroxy-2-(hydroxymethyl);2-HYDROXYMETHYL-5-HYDROXY-4-PYRONE;5-Hydroxy-2-(hydroxymethyl)-γ-pyrone;Kojic acid
CAS:	501-30-4
MF:	C6H6O4
MW:	142.11
EINECS:	207-922-4
Product Categories:	Pyridines;Cosmetics;Chelating Agents & Ligands;Herb extract;inhibitor;Fine Chemical;FINE Chemical & INTERMEDIATES;Heterocycles;Plant Oils, Toxins, Phenolic Acids & Derivatives;organic interm;501-30-4
Mol File:	501-30-4.mol

Kojic acid Chemical Properties

Melting point	152-155 °C (lit.)
Boiling point	179.65°C (rough estimate)
density	1.1712 (rough estimate)
refractive index	1.4434 (estimate)
storage temp.	Store below +30°C.
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
form	Crystalline Powder
pka	7.9(at 25℃)
color	White to beige-brown
Water Solubility	SOLUBLE
λmax	269nm(CHCl3)(lit.)
Merck	14,5317
BRN	120895
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
LogP	-0.640
CAS DataBase Reference	501-30-4(CAS DataBase Reference)
NIST Chemistry Reference	5-Hydroxy-2-(hydroxymethyl)-4h-pyran-4-one(501-30-4)
IARC	3 (Vol. 79) 2001
EPA Substance Registry System	Kojic acid (501-30-4)

Product Usage

kojic acid is a skin-lightening agent that acts through anti-oxidant activity. Kojic acid is a tyrosinase inhibitor, although it is not as effective as licorice extract. When combined with allantoin and other proper ingredients in sunscreen preparations, the mixture can inhibit uV-caused erythema and accelerate wound healing. It is also found to be skin sensitizing and can be irritating.

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