Propylene glycol CAS#57-55-6

Name: Propylene glycol CAS#57-55-6
SKU: 0

Classification：Pharmaceutical Raw Materials

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product description

Propylene glycol

Propylene Glycol USP/EP/FCC (CAS 57-55-6) is a high-purity (>99.5%) multi-functional liquid solvent and humectant compliant with global pharmacopeia standards. As a USP-grade pharmaceutical excipient, it serves as low-endotoxin (≤0.5EU/ml) injection solvent; in cosmetics, it acts as OECD 439-certified low-irritant humectant; for food processing, FCC-grade PG functions as antifreeze carrier (21 CFR 184.1666); while industrial applications leverage its low-toxicity antifreeze properties (-59°C, ASTM D1384). Technical documentation available.

Propylene glycol Chemical Properties

Melting point	-60 °C (lit.)
Boiling point	187 °C (lit.)
density	1.036 g/mL at 25 °C (lit.)
vapor density	2.62 (vs air)
vapor pressure	0.08 mm Hg ( 20 °C)
refractive index	n20/D1.432(lit.)
FEMA	2940 \| PROPYLENE GLYCOL
Fp	225 °F
storage temp.	Store at +5°C to +30°C.
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka	14.49±0.20(Predicted)
form	Viscous Liquid
color	APHA: ≤10
Specific Gravity	1.038 (20/20℃)1.036～1.040
PH	6-8 (100g/l, H2O, 20℃)
Odor	at 100.00 %. odorless very slight alcoholic
Odor Type	odorless
Optical Rotation	-0.11° (C=1.00g/100ml, CHCL3)
biological source	synthetic
explosive limit	2.4-17.4%(V)
Water Solubility	miscible
Sensitive	Hygroscopic
Merck	14,7855
JECFA Number	925
BRN	1340498
Dielectric constant	32.0
InChIKey	DNIAPMSPPWPWGF-UHFFFAOYSA-N
LogP	-0.92
Surface tension	35.44mN/m at 298.15K
CAS DataBase Reference	57-55-6(CAS DataBase Reference)
NIST Chemistry Reference	Propylene glycol(57-55-6)
EPA Substance Registry System	Propylene glycol (57-55-6)

Safety Information

Safety Statements	24/25
WGK Germany	1
RTECS	TY2000000
Autoignition Temperature	779 °F
TSCA	Yes
HS Code	29053200
Hazardous Substances Data	57-55-6(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg

Product Usage

Propylene Glycol (CAS 57-55-6) serves as a vital multifunctional ingredient across industries due to its high solubility and low toxicity. In pharmaceuticals, it acts as a USP-certified solvent for oral/transdermal formulations with low endotoxin levels (≤0.5 EU/ml). Cosmetic manufacturers utilize its OECD 439-certified moisturizing properties in lotions and serums for enhanced hydration. Food processing employs FCC-grade PG as a safe antifreeze carrier (21 CFR 184.1666), while industrial applications leverage its ASTM D1384-compliant antifreeze efficiency (-59°C freeze point). Technical portfolios available for sector-specific solutions.

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